7- (3-Deoxy-β-D-erythro-pentofuranosyl) -7H-pyrrolo[2,3-d]pyrimidin-4-amine
7- (3-Deoxy-β-D-erythro-pentofuranosyl) -7H-pyrrolo[2,3-d]pyrimidin-4-amine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
40725-89-1
UNSPSC
12352005
Hazard Statement
H302-H315-H319
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/7-3-deoxy-β-d-erythro-pentofuranosyl-7h-pyrrolo-2-3-d-pyrimidin-4-amine.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1C[C@@H](O)[C@H](N(C=C2)C3=C2C(N)=NC=N3)O1
Molecular Formula
C11H14N4O3
Molecular Weight
250.25
Precautions
P264-P270-P280-P302+P352-P305+P351+P338-P330-P362+P364-P501
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Frequently Asked Questions
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