INOS inhibitor-10

INOS inhibitor-10 is an iNOS inhibitor (IC50: 65 nM) . iNOS inhibitor-10 has antiproliferative effect against triple negative breast cancer cells[1].

Product Specifications

CAS Number

[2918773-63-2]

UNSPSC

12352005

Target

NO Synthase

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/inos-inhibitor-10.html

Solubility

10 mM in DMSO

Smiles

CC1=CC=C(C=C1)S(=O)(NCC2=CC(CNC(C3=CC=CC=C3)=N)=CC=C2)=O

Molecular Formula

C22H23N3O2S

Molecular Weight

393.50

References & Citations

[1]Carrión MD, et al. New amidine-benzenesulfonamides as iNOS inhibitors for the therapy of the triple negative breast cancer. Eur J Med Chem. 2023 Feb 15;248:115112.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

ENOS; iNOS

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