INOS inhibitor-10
INOS inhibitor-10 is an iNOS inhibitor (IC50: 65 nM) . iNOS inhibitor-10 has antiproliferative effect against triple negative breast cancer cells[1].
Product Specifications
CAS Number
[2918773-63-2]
UNSPSC
12352005
Target
NO Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/inos-inhibitor-10.html
Solubility
10 mM in DMSO
Smiles
CC1=CC=C(C=C1)S(=O)(NCC2=CC(CNC(C3=CC=CC=C3)=N)=CC=C2)=O
Molecular Formula
C22H23N3O2S
Molecular Weight
393.50
References & Citations
[1]Carrión MD, et al. New amidine-benzenesulfonamides as iNOS inhibitors for the therapy of the triple negative breast cancer. Eur J Med Chem. 2023 Feb 15;248:115112.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ENOS; iNOS
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