ATV041
ATV041 is an orally active Ibuprofen and nucleotide analogue. ATV041 improves oral pharmacokinetic (PK) profile and tissue distribution with anti-mouse hepatitis virus (MHV) activity. ATV041 reduces viral load, tissue damage and virus-induced inflammation in a dose-dependent manner[1].
Product Specifications
CAS Number
2935937-67-8
UNSPSC
12352005
Target
HSV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/atv041.html
Solubility
10 mM in DMSO
Smiles
O[C@H]1[C@@H](O)[C@](C#N)(C2=CC=C3C(N)=NC=NN32)O[C@@H]1COC(C(C)C(C=C4)=CC=C4CC(C)C)=O
Molecular Formula
C25H29N5O5
Molecular Weight
479.53
References & Citations
[1]Zhou Q, et al. Nonsteroidal anti-inflammatory drugs (NSAIDs) and nucleotide analog GS-441524 conjugates with potent in vivo efficacy against coronaviruses. Eur J Med Chem. 2023 Jan 10;249:115113.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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