8-Chloro-2’-deoxy-2’-fluoro inosine
8-Chloro-2’-deoxy-2’-fluoro inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/8-chloro-2-deoxy-2-fluoro-inosine.html
Solubility
10 mM in DMSO
Smiles
O=C1C(N=C(Cl)N2[C@H]3[C@H](F)[C@H](O)[C@@H](CO)O3)=C2N=CN1
Molecular Formula
C10H10ClFN4O4
Molecular Weight
304.66
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
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