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8-Chloro-2’-deoxy-2’-fluoro inosine

8-Chloro-2’-deoxy-2’-fluoro inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Product Specifications

UNSPSC

12352005

Target

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/8-chloro-2-deoxy-2-fluoro-inosine.html

Solubility

10 mM in DMSO

Smiles

O=C1C(N=C(Cl)N2[C@H]3[C@H](F)[C@H](O)[C@@H](CO)O3)=C2N=CN1

Molecular Formula

C10H10ClFN4O4

Molecular Weight

304.66

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Curated Selection

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