2-Amino-3’-deoxy-3’-fluoroadenosine
2-Amino-3’-deoxy-3’-fluoroadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
[125391-75-5]
UNSPSC
12352005
Hazard Statement
H315-H319
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/2-amino-3-deoxy-3-fluoroadenosine.html
Solubility
10 mM in DMSO
Smiles
F[C@H]1[C@@H](O)[C@H](N(C=N2)C3=C2C(N)=NC(N)=N3)O[C@@H]1CO
Molecular Formula
C10H13FN6O3
Molecular Weight
284.25
Precautions
P264-P280-P302+P352-P305+P351+P338-P362+P364
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
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