Eleven-Nineteen-Leukemia Protein IN-2
Product Specifications
UNSPSC Description
Eleven-Nineteen-Leukemia Protein IN-2 (compound 23) is an Eleven-Nineteen-Leukemia Protein (ENL) inhibitor with an IC50 value of 10.7 nM. Eleven-Nineteen-Leukemia Protein IN-2 can be used for the research of leukemia[1].
Target Antigen
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/eleven-nineteen-leukemia-protein-in-2.html
Solubility
10 mM in DMSO
Smiles
CC1=NOC2=CC(C(NC3=CC=C4NC(CN5CCC[C@@H]5C)=NC4=C3)=O)=CC=C21
Molecular Weight
389.45
References & Citations
[1]Guo S, et al. Design, synthesis of novel benzimidazole derivatives as ENL inhibitors suppressing leukemia cells viability via downregulating the expression of MYC. Eur J Med Chem. 2023 Feb 15;248:115093.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-152470/Eleven-Nineteen-Leukemia-Protein-IN-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-152470/
Clinical Information
No Development Reported
CAS Number
2894121-78-7
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