3’-Deoxy-3’-fluoro-beta-D-xylo-inosine
3’-Deoxy-3’-fluoro-beta-D-xylo-inosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
171667-46-2
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/3-deoxy-3-fluoro-beta-d-xylo-inosine.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]1[C@@H](F)[C@@H](CO)O[C@H]1N(C=N2)C3=C2C(NC=N3)=O
Molecular Formula
C10H11FN4O4
Molecular Weight
270.22
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
CD31 / PECAM-1 (158-2B3), CF594 conjugate, 0.1mg/mL
Pmel17 / gp100 / SILV (NKI-beteb), CF740 conjugate, 0.1mg/mL
HCG-beta (HCGb/54), CF405S conjugate, 0.1mg/mL
CD79a (B-Cell Marker) (rIGA/764), CF740 conjugate, 0.1mg/mL
