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8-Benzyloxy-9- (β-D-xylofuranosyl) guanine

Selected Variant

HY-152421

Size: 1 Each

8-Benzyloxy-9- (β-D-xylofuranosyl) guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Product Specifications

CAS Number

2389988-19-4

UNSPSC

12352005

Target

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/8-benzyloxy-9-β-d-xylofuranosyl-guanine.html

Solubility

10 mM in DMSO

Smiles

OC[C@@H]1[C@H](O)[C@@H](O)[C@H](N(C(OCC2=CC=CC=C2)=N3)C4=C3C(NC(N)=N4)=O)O1

Molecular Formula

C17H19N5O6

Molecular Weight

389.36

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Price

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