Capromorelin

Capromorelin (CP 424391) is a pyrazolinone-piperidine dipeptide. Capromorelin is an orally active and potent growth hormone secretagogue (GHS) (hGHS-R1a Ki=7 nM, rat pituicyte EC50=3 nM) [1].

Product Specifications

CAS Number

[193273-66-4]

Product Name Alternative

CP 424391

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

GHSR

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology

Assay Protocol

https://www.medchemexpress.com/capromorelin.html

Solubility

10 mM in DMSO

Smiles

CN(C1=O)N=C(CCN(C2)C([C@H](NC(C(C)(N)C)=O)COCC3=CC=CC=C3)=O)[C@]12CC4=CC=CC=C4

Molecular Formula

C28H35N5O4

Molecular Weight

505.61

Precautions

P261-P280-P302+P352

References & Citations

[1]Carpino PA, et al. Pyrazolinone-piperidine dipeptide growth hormone secretagogues (GHSs) . Discovery of capromorelin. Bioorg Med Chem. 2003 Feb 20;11 (4) :581-90.