8-Bromo-9- (β-D-xylofuranosyl) guanine
Selected Variant
HY-152400
Size: 1 Each
8-Bromo-9- (β-D-xylofuranosyl) guanine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
CAS Number
1212650-12-8
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/8-bromo-9-β-d-xylofuranosyl-guanine.html
Solubility
10 mM in DMSO
Smiles
O[C@@H]1[C@@H](O)[C@@H](CO)O[C@H]1N(C(Br)=N2)C3=C2C(NC(N)=N3)=O
Molecular Formula
C10H12BrN5O5
Molecular Weight
362.14
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Price
Frequently Asked Questions
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