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8-Benzyloxy-3’-deoxyguanosine

8-Benzyloxy-3’-deoxyguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Product Specifications

CAS Number

[2389988-57-0]

UNSPSC

12352005

Target

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/8-benzyloxy-3-deoxyguanosine.html

Solubility

10 mM in DMSO

Smiles

OC[C@@H]1C[C@@H](O)[C@H](N2C(OCC3=CC=CC=C3)=NC4=C2NC(N)=NC4=O)O1

Molecular Formula

C17H19N5O5

Molecular Weight

373.36

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

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