7-Ethyl-7,8-dihydro-8-oxo-9- (β-D-xylofuranosyl) guanine
7-Ethyl-7,8-dihydro-8-oxo-9- (β-D-xylofuranosyl) guanine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Product Specifications
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/7-ethyl-7-8-dihydro-8-oxo-9-β-d-xylofuranosyl-guanine.html
Solubility
10 mM in DMSO
Smiles
OC[C@@H]1[C@H](O)[C@@H](O)[C@H](N2C(N(CC)C3=C2NC(N)=NC3=O)=O)O1
Molecular Formula
C12H17N5O6
Molecular Weight
327.29
References & Citations
[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-152328/7-Ethyl-7-8-dihydro-8-oxo-9-β-D-xylofuranosyl-guanine-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-152328/
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
CAS Number
[2389988-43-4]
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