N-[ (3-Methoxyphenyl) methyl]adenosine

N-[ (3-Methoxyphenyl) methyl]adenosine is an adenosine analog. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. Its popular products are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277) [1].

Product Specifications

CAS Number

[101565-95-1]

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-3-methoxyphenyl-methyl-adenosine.html

Solubility

10 mM in DMSO

Smiles

COC1=CC(CNC2=C3C(N([C@@H]4O[C@H](CO)[C@@H](O)[C@H]4O)C=N3)=NC=N2)=CC=C1

Molecular Formula

C18H21N5O5

Molecular Weight

387.39

Precautions

P261-P280-P302+P352

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.|[2]Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26 (6) :1490-1500.