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(1S) -1,4-Anhydro-1-C- (2,4-difluorophenyl) -D-ribitol

(1S) -1,4-Anhydro-1-C- (2,4-difluorophenyl) -D-ribitol is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Product Specifications

CAS Number

263701-23-1

UNSPSC

12352005

Target

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/1s-1-4-anhydro-1-c-2-4-difluorophenyl-d-ribitol.html

Solubility

10 mM in DMSO

Smiles

O[C@H]1[C@@H](O)[C@H](C2=C(F)C=C(F)C=C2)O[C@@H]1CO

Molecular Formula

C11H12F2O4

Molecular Weight

246.21

References & Citations

[1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18 (23) :3373-88.

Shipping Conditions

Room temperature

Scientific Category

Oligonucleotides

Clinical Information

No Development Reported

Frequently Asked Questions

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