Physachenolide C
Product Specifications
CAS Number
791117-61-8
UNSPSC Description
Physachenolide C is a potent and selective BET inhibitor that induces apoptosis and arrests the cell cycle in the G0-G1 phase, with antitumor activity[1].
Target Antigen
Epigenetic Reader Domain
Type
Natural Products
Related Pathways
Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/physachenolide-c.html
Solubility
10 mM in DMSO
Smiles
C[C@]12[C@@]3(CC=CC2=O)[C@](C[C@]4([H])[C@]1([H])CC[C@]5([C@]4(CC[C@@]5(O)[C@@](O)([C@@]6([H])CC(C)=C(C(O6)=O)C)C)O)COC(C)=O)([H])O3
Molecular Weight
544.63
References & Citations
[1]Anngela C Adams, et al. Physachenolide C induces complete regression of established murine melanoma tumors via apoptosis and cell cycle arrest. Transl Oncol. 2022 Jan;15(1):101259.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
Frequently Asked Questions
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