HDAC6-IN-15
HDAC6-IN-15 is a selective histone deacetylase 6 (HDAC6) inhibitor. HDAC6-IN-15 has potent inhibitory activity for HDAC6 with IC50 value of 38.2 nM. HDAC6-IN-15 can be used for the research of cancer and neurodegenerative diseases[1].
Product Specifications
UNSPSC
12352300
Target
HDAC
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/hdac6-in-15.html
Solubility
10 mM in DMSO
Smiles
[][Fe][].FC(C=C(C(NO)=O)C=C1)=C1CN(CC2)CCN2C(CCc3cccc3)c4cccc4
Molecular Formula
C25H28FFeN3O2
Molecular Weight
477.35
References & Citations
[1]Jiangkun Yan, et al. Synthesis and bioactivity evaluation of ferrocene-based hydroxamic acids as selective histone deacetylase 6 inhibitors. Eur J Med Chem. 2023 Jan 15;246:115004.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC6
Frequently Asked Questions
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