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HDAC6-IN-15

HDAC6-IN-15 is a selective histone deacetylase 6 (HDAC6) inhibitor. HDAC6-IN-15 has potent inhibitory activity for HDAC6 with IC50 value of 38.2 nM. HDAC6-IN-15 can be used for the research of cancer and neurodegenerative diseases[1].

Product Specifications

UNSPSC

12352300

Target

HDAC

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/hdac6-in-15.html

Solubility

10 mM in DMSO

Smiles

[][Fe][].FC(C=C(C(NO)=O)C=C1)=C1CN(CC2)CCN2C(CCc3cccc3)c4cccc4

Molecular Formula

C25H28FFeN3O2

Molecular Weight

477.35

References & Citations

[1]Jiangkun Yan, et al. Synthesis and bioactivity evaluation of ferrocene-based hydroxamic acids as selective histone deacetylase 6 inhibitors. Eur J Med Chem. 2023 Jan 15;246:115004.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

HDAC6

Frequently Asked Questions

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