BChE-IN-15
BChE-IN-15 (Compound 6) is a pseudo-irreversible and covalent BChE inhibitor with an IC50 of 1.76 nM against hBChE [1].
Product Specifications
UNSPSC
12352005
Target
Cholinesterase (ChE)
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bche-in-15.html
Solubility
10 mM in DMSO
Smiles
CN(CC1=CNC2=C(C=CC=C12)OC(N(C)C)=O)CCC3CCCCCC3
Molecular Formula
C22H33N3O2
Molecular Weight
371.52
References & Citations
[1]Meden A, et al. Pseudo-irreversible butyrylcholinesterase inhibitors: Structure-activity relationships, computational and crystallographic study of the N-dialkyl O-arylcarbamate warhead. Eur J Med Chem. 2022 Dec 24;247:115048.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; BChE
Frequently Asked Questions
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