SPR41

SPR41 is a potent SARS-CoV-2 main protease inhibitor with Ki values of 0.184, 0.252, 14.4 µM for SARS-CoV-2 Mpro, hCatL, hCatB, respectively. SPR41 shows antiviral and cytotoxicity[1].

Product Specifications

UNSPSC

12352005

Target

SARS-CoV

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/spr41.html

Solubility

10 mM in DMSO

Smiles

O=C(OCC1=CC=CC=C1)N[C@@H](CC2CCCCC2)C(N[C@H](/C=C/C(C)=O)C[C@H]3C(NCC3)=O)=O

Molecular Formula

C27H37N3O5

Molecular Weight

483.60

References & Citations

[1]Previti S, et al. Structure-based lead optimization of peptide-based vinyl methyl ketones as SARS-CoV-2 main protease inhibitors. Eur J Med Chem. 2022 Dec 15;247:115021.