SPR39
SPR39 is a potent SARS-CoV-2 main protease inhibitor with Ki values of 0.252, 3.38, 7.88 µM for SARS-CoV-2 Mpro, hCatL, hCatB, respectively. SPR39 shows antiviral and cytotoxicity[1].
Product Specifications
UNSPSC
12352005
Target
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/spr39.html
Solubility
10 mM in DMSO
Smiles
O=C(OCC1=CC=CC=C1)N[C@@H](CC2CC2)C(N[C@H](/C=C/C(C)=O)C[C@H]3C(NCC3)=O)=O
Molecular Formula
C24H31N3O5
Molecular Weight
441.52
References & Citations
[1]Previti S, et al. Structure-based lead optimization of peptide-based vinyl methyl ketones as SARS-CoV-2 main protease inhibitors. Eur J Med Chem. 2022 Dec 15;247:115021.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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