Mitochondrial respiration-IN-2

Mitochondrial respiration-IN-2 is the fluorine derivative of Virginiamycin M1 (HY-N6686) . Mitochondrial respiration-IN-2 can inhibit mitochondrial translation of glioblastoma stem cells[1].

Product Specifications

CAS Number

[318498-81-6]

UNSPSC

12352005

Target

Drug Derivative

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mitochondrial-respiration-in-2.html

Solubility

10 mM in DMSO

Smiles

O=C(O[C@@H]([C@@H](/C=C/C(NC/C=C/C(C)=C/[C@H](C[C@H](CC1=NC2=CO1)F)O)=O)C)C(C)C)C3=CCCN3C2=O

Molecular Formula

C28H36FN3O6

Molecular Weight

529.60

References & Citations

[1]Denise Sighel, et al. Streptogramin A derivatives as mitochondrial translation inhibitors to suppress glioblastoma stem cell growth. Eur J Med Chem. 2023 Jan 15;246:114979.