Mitochondrial respiration-IN-3

Mitochondrial respiration-IN-3 is the fluorine derivative of Dalfopristin (HY-A0241) . Mitochondrial respiration-IN-3 has cell membrane-permeable. Mitochondrial respiration-IN-3 can inhibit mitochondrial translation of glioblastoma stem cells. Mitochondrial respiration-IN-3 can be used in research of cancer[1].

Product Specifications

UNSPSC

12352005

Target

Mitochondrial Metabolism

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/mitochondrial-respiration-in-3.html

Solubility

10 mM in DMSO

Smiles

O=S([C@H]1[C@@]2(C(O[C@H](C(C)C)[C@H](C)/C=C/C(NC/C=C/C(C)=C/[C@@H](O)C[C@@H](F)CC3=NC(C(N2CC1)=O)=CO3)=O)=O)[H])(CCN(CC)CC)=O

Molecular Formula

C34H51FN4O8S

Molecular Weight

694.85

References & Citations

[1]Sighel D, et, al. Streptogramin A derivatives as mitochondrial translation inhibitors to suppress glioblastoma stem cell growth. Eur J Med Chem. 2023 Jan 15;246:114979.