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HIV-1 inhibitor-53

HIV-1 inhibitor-53 is a dual HIV-1 protease and reverse transcriptase inhibitor. HIV-1 inhibitor-53 inhibits HIV-1 protease (PR) and reverse transcriptase (RT) activity with IC50 values of 1.93 nM and 2.35 μM, respectively. HIV-1 inhibitor-53 can be used for the research of acquired immune deficiency syndrome (AIDS) [1].

Product Specifications

CAS Number

[2883496-10-2]

UNSPSC

12352005

Target

HIV Protease; Reverse Transcriptase

Type

Reference compound

Related Pathways

Anti-infection; Metabolic Enzyme/Protease

Applications

COVID-19-anti-virus

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/hiv-1-inhibitor-53.html

Solubility

10 mM in DMSO

Smiles

COC1=CC=C(C=C1)S(=O)(N(C[C@H]([C@@H](NC(C2=CC3=C(O2)C=C(C(O)=C3)O)=O)CC4=CC=CC=C4)O)CC(C)C)=O

Molecular Formula

C30H34N2O8S

Molecular Weight

582.66

References & Citations

[1]Mei Zhu, Structure based design and evaluation of benzoheterocycle derivatives as potential dual HIV-1 protease and reverse transcriptase inhibitors. Eur J Med Chem

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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