HIV-1 inhibitor-53
Product Specifications
UNSPSC Description
HIV-1 inhibitor-53 is a dual HIV-1 protease and reverse transcriptase inhibitor. HIV-1 inhibitor-53 inhibits HIV-1 protease (PR) and reverse transcriptase (RT) activity with IC50 values of 1.93 nM and 2.35 μM, respectively. HIV-1 inhibitor-53 can be used for the research of acquired immune deficiency syndrome (AIDS)[1].
Target Antigen
HIV Protease; Reverse Transcriptase
Type
Reference compound
Related Pathways
Anti-infection;Metabolic Enzyme/Protease
Applications
COVID-19-anti-virus
Field of Research
Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/hiv-1-inhibitor-53.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(C=C1)S(=O)(N(C[C@H]([C@@H](NC(C2=CC3=C(O2)C=C(C(O)=C3)O)=O)CC4=CC=CC=C4)O)CC(C)C)=O
Molecular Weight
582.66
References & Citations
[1]Mei Zhu, Structure based design and evaluation of benzoheterocycle derivatives as potential dual HIV-1 protease and reverse transcriptase inhibitors. Eur J Med Chem
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-152200/HIV-1-inhibitor-53-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-152200/
Clinical Information
No Development Reported
CAS Number
2883496-10-2
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