AMPD2 inhibitor 2
Product Specifications
UNSPSC Description
AMPD2 inhibitor 2 (compound 21) is a potent AMP deaminase 2 (AMPD2) inhibitor with IC50s of 0.1 μM and 0.28μM for hAMPD2 and mAMPD2, respectively. AMPD2 inhibitor 2 has the potential for evaluating the physiological role of AMPD2 in mice maintained on a high fat diet[1].
Target Antigen
Adenosine Deaminase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/ampd2-inhibitor-2.html
Solubility
10 mM in DMSO
Smiles
CC1(CN(C2=CC=C(C(F)=C2N1CC3=CC=C(C=C3)COC4=CC=C(C=C4)CO)F)C(N)=O)C
Molecular Weight
467.51
References & Citations
[1]Yuki Kitao, et al. The discovery of 3,3-dimethyl-1,2,3,4-tetrahydroquinoxaline-1-carboxamides as AMPD2 inhibitors with a novel mechanism of action. Bioorg Med Chem Lett. 2022 Dec 20;80:129110.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-152199/AMPD2-inhibitor-2-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-152199/
Clinical Information
No Development Reported
CAS Number
3026893-31-9
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS6192179-01 0.1 mL
RAPGEF3 (CGEF1, EPAC, EPAC1, Rap Guanine Nucleotide Exchange Factor 3, Exchange Factor Directly Activated by cAMP 1, Exchange Protein Directly Activated by cAMP 1, Rap1 Guanine-nucleotide-exchange Factor Directly Activated by cAMP, cAMP-regulated Guanine
Ask
View Details MBS6192179-02 5x 0.1 mL
RAPGEF3 (CGEF1, EPAC, EPAC1, Rap Guanine Nucleotide Exchange Factor 3, Exchange Factor Directly Activated by cAMP 1, Exchange Protein Directly Activated by cAMP 1, Rap1 Guanine-nucleotide-exchange Factor Directly Activated by cAMP, cAMP-regulated Guanine
Ask
View Details ![Granulocytes + Monocytes Mouse Monoclonal Antibody [Clone ID: 74-22-15]](https://cdn.genprice.uk/products/937/68dd189a061270361e8fc17f/imageurl/am08108fc-n.webp)
AM08108FC-N 500 µg
Granulocytes + Monocytes Mouse Monoclonal Antibody [Clone ID: 74-22-15]
Ask
View Details