Tankyrase-IN-4
Tankyrase-IN-4 is a tankyrase 1 (TNKS1) inhibitor with an IC50 value of 0.8 nM. Tankyrase-IN-4 can be used for the research of cancer[1].
Product Specifications
UNSPSC
12352005
Target
PARP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tankyrase-in-4.html
Solubility
10 mM in DMSO
Smiles
CNC([C@@H](NC(C1=CN=C2C=CC=CC2=C1)=O)CNC(CCN3C(NC(C4=C3C=CC=C4)=O)=O)=O)=O
Molecular Formula
C25H24N6O5
Molecular Weight
488.50
References & Citations
[1]Alba L Montoya, et al. Combining pharmacophore models derived from DNA-encoded chemical libraries with structure-based exploration to predict Tankyrase 1 inhibitors. Eur J Med Chem. 2023 Jan 15;246:114980.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
TNKS1/PARP5A
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![[2-[[3-(2-Chlorobenzoyl)-5-ethyl-2-thienyl]amino]-2-oxoethyl]carbamic Acid Benzyl Ester](https://cdn.genprice.uk/products/572/1175270972372/imageurl/trc-c364970-1g.webp)
TRC-C364970-1G 1 g
[2-[[3-(2-Chlorobenzoyl)-5-ethyl-2-thienyl]amino]-2-oxoethyl]carbamic Acid Benzyl Ester
Sign In for Pricing
View Details 
TRC-C171361-500MG 500 mg
2-(3-Chlorophenyl)pyrimidine-4-carboxylic Acid
Sign In for Pricing
View Details 