SEW84
SEW84 is an inhibitor of Aha1-stimulated Hsp90 (ASH) ATPase activity. SEW84 inhibits Aha1-stimulated Hsp90 (ASH) activity with an IC50 value of 0.3 μM. SEW84 can be used in the study of protein deposition diseases[1].
Product Specifications
CAS Number
259089-67-3
Product Name Alternative
SEW04784
UNSPSC
12352005
Target
HSP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/sew84.html
Purity
99.73
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=CN1C2=CC=C(C=C2)F)NNC(NC3=CC=CC(C(F)(F)F)=C3)=S
Molecular Formula
C19H14F4N4OS
Molecular Weight
422.40
References & Citations
[1]Jay K Singh, et al. Management of Hsp90-Dependent Protein Folding by Small Molecules Targeting the Aha1 Co-Chaperone. Cell Chem Biol. 2020 Mar 19;27 (3) :292-305.e6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
MBS1490093-01 0.05 mg
Rabbit anti-mouse B-lymphocyte antigen CD20 polyclonal Antibody, HRP conjugated
Sign In for Pricing
View Details MBS1490093-02 0.1 mg
Rabbit anti-mouse B-lymphocyte antigen CD20 polyclonal Antibody, HRP conjugated
Sign In for Pricing
View Details MBS1490093-03 5x 0.1 mg
Rabbit anti-mouse B-lymphocyte antigen CD20 polyclonal Antibody, HRP conjugated
Sign In for Pricing
View Details K6387708 1.0 µg DNA
Fbxo48 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 3)
Sign In for Pricing
View Details 
AM0472 2 OD, 4 OD, 50 OD
MIRacle™ hsa-miR-4713-5p miRNA Agomir/Antagomir
Sign In for Pricing
View Details