SEW84
SEW84 is an inhibitor of Aha1-stimulated Hsp90 (ASH) ATPase activity. SEW84 inhibits Aha1-stimulated Hsp90 (ASH) activity with an IC50 value of 0.3 μM. SEW84 can be used in the study of protein deposition diseases[1].
Product Specifications
CAS Number
259089-67-3
Product Name Alternative
SEW04784
UNSPSC
12352005
Target
HSP
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/sew84.html
Purity
99.73
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=CN1C2=CC=C(C=C2)F)NNC(NC3=CC=CC(C(F)(F)F)=C3)=S
Molecular Formula
C19H14F4N4OS
Molecular Weight
422.40
References & Citations
[1]Jay K Singh, et al. Management of Hsp90-Dependent Protein Folding by Small Molecules Targeting the Aha1 Co-Chaperone. Cell Chem Biol. 2020 Mar 19;27 (3) :292-305.e6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
K2470807 1.0 µg DNA
TRIP13 sgRNA CRISPR/Cas9 All-in-One Lentivector (Human) (Target 2)
Sign In for Pricing
View Details 41362061 1.0 µg DNA
RPL31P22 Lentiviral Vector (Human) (CMV) (pLenti-GIII-CMV)
Sign In for Pricing
View Details 