Antibacterial agent 130
Product Specifications
UNSPSC Description
Antibacterial agent 130 is a 1,1-diarylthiogalactoside, used for targeting the Pseudomonas aeruginosa LecA. Antibacterial agent 130 shows high affinity toward LecA (Kd=1 μM). Antibacterial agent 130 has antibiofilm activity, but lacks bactericidal activity. LecA, a lectin and virulence factor from Pseudomonas aeruginosa involved in bacterial adhesion and biofilm formation[1].
Target Antigen
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antibacterial-agent-130.html
Solubility
10 mM in DMSO
Smiles
OC[C@H]1O[C@@H](SC2=C(OC)C=CC(C(C3=CC(OC)=C(OC)C(OC)=C3)=O)=C2)[C@H](O)[C@@H](O)[C@H]1O
Molecular Weight
496.53
References & Citations
[1]Bruneau A, et al. Discovery of potent 1,1-diarylthiogalactoside glycomimetic inhibitors of Pseudomonas aeruginosa LecA with antibiofilm properties. Eur J Med Chem. 2022 Dec 15;247:115025.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-152175/Antibacterial-agent-130-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-152175/
Clinical Information
No Development Reported
CAS Number
9007-83-4
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