TJ08
TJ08, a 1,2,5-trisubstituted benzimidazole derivative, efficiently induces G1/S phase arrest and promotes apoptosis in various cancer cells. TJ08 is an anticancer agent[1].
Product Specifications
CAS Number
2924274-19-9
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tj08.html
Solubility
10 mM in DMSO
Smiles
COC(C1=CC=C2C(N=C(N2CC3=CC=CC=C3)C4=CC=C(C([N+]([O-])=O)=C4)F)=C1)=O
Molecular Formula
C22H16FN3O4
Molecular Weight
405.38
References & Citations
[1]Jagadeesha Gullahalli Swathantraiah, et al. Novel 1,2,5-Trisubstituted Benzimidazoles Potentiate Apoptosis by Mitochondrial Dysfunction in Panel of Cancer Cells. ACS Omega. 2022 Dec 6;7 (50) :46955-46971.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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