AChE/BChE/MAO-B-IN-3
AChE/BChE/MAO-B-IN-3, an indan-1-one derivative, is a potent MAO-B inhibitor with an IC50 of 0.0359 μM for human MAO-B. AChE/BChE/MAO-B-IN-3 is a potent AChE and BChE enzyme inhibitor, with IC50s of 0.0473 μM and 0.0782 μM for human AChE and BChE enzyme, respectively. AChE/BChE/MAO-B-IN-3 shows significant antioxidant activity and has the potential for Alzheimer's disease (AD) research[1].
Product Specifications
UNSPSC
12352005
Target
Cholinesterase (ChE) ; Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-bche-mao-b-in-3.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(/C=C(CC2=C3C=C(OC)C=C2)/C3=O)C=C1)CN(C)CCCN(C)C
Molecular Formula
C25H31N3O3
Molecular Weight
421.53
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; BChE; MAO-B
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