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AChE/BChE/MAO-B-IN-2

AChE/BChE/MAO-B-IN-2 is a potent AChE, BChE, and MAO-B enzymes inhibitor with IC50 values of 48.2 nM, 83.9 nM, and 31.2 nM, respectively. AChE/BChE/MAO-B-IN-2 has significant antioxidant activity, and can be used for Parkinson’s disease research[1].

Product Specifications

UNSPSC

12352005

Target

Cholinesterase (ChE) ; Monoamine Oxidase

Type

Reference compound

Related Pathways

Neuronal Signaling

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/ache-bche-mao-b-in-2.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=CC=C(/C=C(CC2=C3C=CC(OC)=C2)\C3=O)C=C1)CN(C)CCCN(C)C

Molecular Formula

C25H31N3O3

Molecular Weight

421.53

References & Citations

[1]Begüm Nurpelin Sağlık, et al. Design, Synthesis, and In Vitro and In Silico Approaches of Novel Indanone Derivatives as Multifunctional Anti-Alzheimer Agents. ACS Omega. 2022 Dec 7;7 (50) :47378-47404.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

AChE; BChE; MAO-B

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