AChE/MAO-IN-1
AChE/MAO-IN-1 (Compound D28) is a potent AChE, MAO-A and MAO-B inhibitor with IC50s of 0.0248, 0.0409 and 0.1108 μM against human AChE, MAO-B and MAO-A, respectively[1].
Product Specifications
UNSPSC
12352005
Target
Amyloid-β; Cholinesterase (ChE) ; Monoamine Oxidase
Type
Reference compound
Related Pathways
Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/ache-mao-in-1.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=CC=C(/C=C(CC2=C3C=CC(OC)=C2)\C3=O)C=C1)CN(C)CCC
Molecular Formula
C23H26N2O3
Molecular Weight
378.46
References & Citations
[1]Sağlık BN, et al. Design, Synthesis, and In Vitro and In Silico Approaches of Novel Indanone Derivatives as Multifunctional Anti-Alzheimer Agents. ACS Omega. 2022 Dec 7;7 (50) :47378-47404.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
AChE; MAO-A; MAO-B
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