SARS-CoV-2 Mpro-IN-6
SARS-CoV-2 Mpro-IN-6 is a covalent, irreversible and selective SARS-CoV-2 Mpro inhibitor with an IC50 of 0.18 μM. SARS-CoV-2 Mpro-IN-6 does not inhibit human cathepsins B, F, K, and L, and caspase 3[1].
Product Specifications
CAS Number
2768834-48-4
UNSPSC
12352005
Target
SARS-CoV
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/sars-cov-2-mpro-in-6.html
Solubility
10 mM in DMSO
Smiles
O=C([C@H]1N(C2=CC=C(Cl)C(Cl)=C2)CCN(C(CCl)=O)C1)NCC3=CC=CS3
Molecular Formula
C18H18Cl3N3O2S
Molecular Weight
446.78
References & Citations
[1]Shenghua Gao, et al. Discovery and Crystallographic Studies of Nonpeptidic Piperazine Derivatives as Covalent SARS-CoV-2 Main Protease Inhibitors. J Med Chem. 2022 Dec 22;65 (24) :16902-16917.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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