SB26019
SB26019 is a potent anti-neuroinflammatory agent. SB26019 regulates NF-κB activation by inducing monomeric α-tubulin formation. SB26019-induced α-tubulin monomer inhibits p65 translocation[1].
Product Specifications
CAS Number
1233078-90-4
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
COVID-19-anti-virus
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sb26019.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C2C(C3=C4OC5=C(C4=CC=C3)C=CC=C5)=CC(C)(OC2=C1O)C
Molecular Formula
C24H20O4
Molecular Weight
372.41
References & Citations
[1]Junhyeong Yim, et al. Phenotype-based screening rediscovered benzopyran-embedded microtubule inhibitors as anti-neuroinflammatory agents by modulating the tubulin-p65 interaction. Exp Mol Med. 2022 Dec 12;1-10.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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