DCZ19931
DCZ19931 is a potent multi-targeting kinase inhibitor. DCZ19931 has anti-angiogenic effects on ocular neovascularization. DCZ19931 also inhibits ERK1/2-MAPK and p38-MAPK signaling[1].
Product Specifications
CAS Number
2789629-84-9
UNSPSC
12352005
Target
ERK; p38 MAPK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway; Stem Cell/Wnt
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/dcz19931.html
Solubility
10 mM in DMSO
Smiles
COC1=CC(NC(C(F)(C2=CC=C(C=C2)OC3=C4C=C(C(OC)=CC4=NC=N3)OC)F)=O)=CC(C(F)(F)F)=C1
Molecular Formula
C26H20F5N3O5
Molecular Weight
549.45
References & Citations
[1]Zhang H, et al. DCZ19931, a novel multi-targeting kinase inhibitor, inhibits ocular neovascularization. Sci Rep. 2022 Dec 13;12 (1) :21539.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
ERK1; ERK2; p38 MAPK
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