Telomerase-IN-5
Telomerase-IN-5 is a potent telomerase inhibitor. Telomerase-IN-5 has antiproliferative activity and induces apoptosis[1].
Product Specifications
CAS Number
[2892295-16-6]
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/telomerase-in-5.html
Solubility
10 mM in DMSO
Smiles
O=C(NC1=C(C#N)C2=C(CCCC2)S1)CSC3=NN=C(C4=CC=C(C)C=C4)C=C3
Molecular Formula
C22H20N4OS2
Molecular Weight
420.55
References & Citations
[1]Al-Karmalawy AA, et, al. Ligand-Based Design on the Dog-Bone-Shaped BIBR1532 Pharmacophoric Features and Synthesis of Novel Analogues as Promising Telomerase Inhibitors with In Vitro and In Vivo Evaluations. J Med Chem. 2022 Dec 16.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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