Telomerase-IN-5

Telomerase-IN-5 is a potent telomerase inhibitor. Telomerase-IN-5 has antiproliferative activity and induces apoptosis[1].

Product Specifications

CAS Number

[2892295-16-6]

UNSPSC

12352005

Target

Apoptosis

Type

Reference compound

Related Pathways

Apoptosis

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/telomerase-in-5.html

Solubility

10 mM in DMSO

Smiles

O=C(NC1=C(C#N)C2=C(CCCC2)S1)CSC3=NN=C(C4=CC=C(C)C=C4)C=C3

Molecular Formula

C22H20N4OS2

Molecular Weight

420.55

References & Citations

[1]Al-Karmalawy AA, et, al. Ligand-Based Design on the Dog-Bone-Shaped BIBR1532 Pharmacophoric Features and Synthesis of Novel Analogues as Promising Telomerase Inhibitors with In Vitro and In Vivo Evaluations. J Med Chem. 2022 Dec 16.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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