Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

URAT1 inhibitor 4

URAT1 inhibitor 4, a Lesinurad derivative, is a potent and orally active URAT1 inhibitor with an IC50 of 7.56 μM. URAT1 inhibitor 4 has higher in vivo urate-lowering efficacy than Lesinurad (HY-15258) [1].

Product Specifications

CAS Number

[2700292-02-8]

UNSPSC

12352005

Target

GLUT; URAT1

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/urat1-inhibitor-4.html

Solubility

10 mM in DMSO

Smiles

O=C(NS(=O)(C1=CC=C(C=C1)Br)=O)CSC2=NC3=C(C(N2C4=CC=C(C5=C4C=CC=C5)C6CC6)=O)C=CS3

Molecular Formula

C27H20BrN3O4S3

Molecular Weight

626.56

References & Citations

[1]Zhang J, et al. Design, synthesis and activity evaluation of novel lesinurad analogues containing thienopyrimidinone or pyridine substructure as human urate transporter 1 inhibitors. Eur J Med Chem. 2022 Dec 15;244:114816.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

More Discoveries

Explore Other Products

Browse additional items from our catalog

TOMM40 Antibody
A37220-50UL 50 μL

TOMM40 Antibody

Sign In for Pricing
View Details
Cullin 4A Rabbit pAb
E47R3642 100 µL

Cullin 4A Rabbit pAb

Sign In for Pricing
View Details
Dextrose Azide Broth
DHDAB-0500 500 g

Dextrose Azide Broth

Sign In for Pricing
View Details
CD86 (T-lymphocyte Activation Antigen CD86, Activation B7-2 Antigen, B70, BU63, CTLA-4 Counter-receptor B7.2, FUN-1, CD28LG2) APC
MBS6135781-01 0.1 mL

CD86 (T-lymphocyte Activation Antigen CD86, Activation B7-2 Antigen, B70, BU63, CTLA-4 Counter-receptor B7.2, FUN-1, CD28LG2) APC

Sign In for Pricing
View Details
CD86 (T-lymphocyte Activation Antigen CD86, Activation B7-2 Antigen, B70, BU63, CTLA-4 Counter-receptor B7.2, FUN-1, CD28LG2) APC
MBS6135781-02 5x 0.1 mL

CD86 (T-lymphocyte Activation Antigen CD86, Activation B7-2 Antigen, B70, BU63, CTLA-4 Counter-receptor B7.2, FUN-1, CD28LG2) APC

Sign In for Pricing
View Details
Lentiviral mouse Mmp9 shRNA (UAS) - Lentiviral mouse Mmp9 shRNA (UAS, RFP) (25)
GTR15232367 1 Vial

Lentiviral mouse Mmp9 shRNA (UAS) - Lentiviral mouse Mmp9 shRNA (UAS, RFP) (25)

Sign In for Pricing
View Details