Xanthine oxidoreductase-IN-4

Xanthine oxidoreductase-IN-4 is an orally active xanthine oxidoreductase (XOR) inhibitor. Xanthine oxidoreductase-IN-4 has inhibitory activity against XOR with an IC50 value of 29.3 nM. Xanthine oxidoreductase-IN-4 can be used for the research of hyperuricemia[1].

Product Specifications

CAS Number

[1026587-58-5]

UNSPSC

12352005

Hazard Statement

H228-H315-H319

Target

Xanthine Oxidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/xanthine-oxidoreductase-in-4.html

Solubility

10 mM in DMSO

Smiles

CCOC1=CC=C(C=C1)NC(C2=CC=C(C=C2)C3=NN=NN3)=O

Molecular Formula

C16H15N5O2

Molecular Weight

309.32

Precautions

P210-P240-P241-P264-P280-P302+P352-P305+P351+P338-P362+P364-P370+P378

References & Citations

[1]Wen Peng, et al. Design, synthesis, and evaluation of tricyclic compounds containing phenyl-tetrazole as XOR inhibitors. Eur J Med Chem. 2022 Nov 28;246:114947.