Xanthine oxidoreductase-IN-3

Xanthine oxidoreductase-IN-3 is an orally active xanthine oxidoreductase (XOR) inhibitor, with an IC50 of 26.3 nM. Xanthine oxidoreductase-IN-3 can be used for the research of acute hyperuricemia[1].

Product Specifications

CAS Number

[651769-78-7]

UNSPSC

12352005

Hazard Statement

H228-H315-H319

Target

Xanthine Oxidase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/xanthine-oxidoreductase-in-3.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC=C(C=C1)C2=NN=NN2)NC3=CC=C(C=C3)Cl

Molecular Formula

C14H10ClN5O

Molecular Weight

299.72

Precautions

P210-P240-P241-P264-P280-P302+P352-P305+P351+P338-P362+P364-P370+P378

References & Citations

[1]Peng W, et, al. Design, synthesis, and evaluation of tricyclic compounds containing phenyl-tetrazole as XOR inhibitors. Eur J Med Chem. 2022 Nov 28;246:114947.