Antitubercular agent-36

Antitubercular agent-36 (compound 53) is an antitubercular agent. Antitubercular agent-36 inhibits the growth of MtbH37Rv with a MIC90 value of 1.25 μg/mL. Antitubercular agent-36 can be used for the research of tuberculosis[1].

Product Specifications

CAS Number

2883173-82-6

UNSPSC

12352005

Target

Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antitubercular-agent-36.html

Solubility

10 mM in DMSO

Smiles

CCOC(C1=NOC(C2=NC(NC3=CC=C(C=C3)C)=CC=C2)=C1)=O

Molecular Formula

C18H17N3O3

Molecular Weight

323.35

References & Citations

[1]Girardini M, et al. Expanding the knowledge around antitubercular 5- (2-aminothiazol-4-yl) isoxazole-3-carboxamides: Hit-to-lead optimization and release of a novel antitubercular chemotype via scaffold derivatization. Eur J Med Chem. 2023 Jan 5;245 (Pt 2) :114916.