Antitubercular agent 34
Antitubercular agent 34 (compound 42g) is an antitubercular agent. Antitubercular agent 34 inhibits the growth of MtbH37Rv with a MIC90 value of 1.25 μg/mL with the ability of escaping metabolic degradation by human liver microsomes. Antitubercular agent 34 can be used for the research of tuberculosis[1].
Product Specifications
CAS Number
2883173-23-5
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antitubercular-agent-34.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NOC(C2=CSC(NC3=CC=CC=C3)=N2)=C1)NC4=CC=CC=C4
Molecular Formula
C19H14N4O2S
Molecular Weight
362.41
References & Citations
[1]Girardini M, et al. Expanding the knowledge around antitubercular 5- (2-aminothiazol-4-yl) isoxazole-3-carboxamides: Hit-to-lead optimization and release of a novel antitubercular chemotype via scaffold derivatization. Eur J Med Chem. 2023 Jan 5;245 (Pt 2) :114916.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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