Antitubulin agent 1
Antitubulin agents-1 is an antitubulin agent that induces disruption of the microtubules (Microtubule/Tubulin) and increases α-tubulin acetylation. Antitubulin agents-1 has anticancer effects[1]. Antitubulin agent 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352005
Target
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/antitubulin-agent-1.html
Solubility
10 mM in DMSO
Smiles
C#CCOC1=CC(N/C(C)=C2C(NN(C\2=O)CC3=CC=CC=C3)=O)=CC=C1
Molecular Formula
C21H19N3O3
Molecular Weight
361.39
References & Citations
[1]Arash Foroutan, et al. Identification of novel aza-analogs of TN-16 as disrupters of microtubule dynamics through a multicomponent reaction. Eur J Med Chem. 2023 Jan 5;245 (Pt 1) :114895.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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