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ALR2-IN-2

Product Specifications

UNSPSC Description

ALR2-IN-2 is a potent inhibitor of aldose reductase (ALR2), with IC50s of 27 nM and 228 nM for rat ALR2 and ALR1, respectively. ALR2-IN-2 can be used for the research of diabetic complications[1].

Target Antigen

Aldose Reductase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/alr2-in-2.html

Solubility

10 mM in DMSO

Smiles

FC1=CC=C(C=C1)/C=N/N2C(/C(SC2=S)=C/C3=CC=C(C=C3)O)=O

Molecular Weight

358.41

References & Citations

[1]Kratky M, et, al. Novel rhodanine based inhibitors of aldose reductase of non-acidic nature with p-hydroxybenzylidene functional group. Eur J Med Chem. 2022 Nov 12;246:114922.

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-151946/ALR2-IN-2-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-151946/

Clinical Information

No Development Reported

Curated Selection

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