ALR2-IN-2
ALR2-IN-2 is a potent inhibitor of aldose reductase (ALR2), with IC50s of 27 nM and 228 nM for rat ALR2 and ALR1, respectively. ALR2-IN-2 can be used for the research of diabetic complications[1].
Product Specifications
UNSPSC
12352005
Target
Aldose Reductase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Metabolism-sugar/lipid metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/alr2-in-2.html
Solubility
10 mM in DMSO
Smiles
FC1=CC=C(C=C1)/C=N/N2C(/C(SC2=S)=C/C3=CC=C(C=C3)O)=O
Molecular Formula
C17H11FN2O2S2
Molecular Weight
358.41
References & Citations
[1]Kratky M, et, al. Novel rhodanine based inhibitors of aldose reductase of non-acidic nature with p-hydroxybenzylidene functional group. Eur J Med Chem. 2022 Nov 12;246:114922.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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