Antibacterial agent 128

Antibacterial agent 128 is a siderophore analog-Ciprofloxacin (HY-B0356) conjugate with a cleavable linker. Antibacterial agent 128 shows antibiotic activities against P. aeruginosa (MIC values of 0.25-64 μg/mL) and B. pseudomallei (MIC values of 1-32 μg/mL) [1].

Product Specifications

CAS Number

[3059046-75-9]

UNSPSC

12352005

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/antibacterial-agent-128.html

Solubility

10 mM in DMSO

Smiles

CC(OC(N1CCN(CC1)C2=CC3=C(C(C(C(O)=O)=CN3C4CC4)=O)C=C2F)=O)OC(C5=CC(C(O)=CN5)=O)=O

Molecular Formula

C26H25FN4O9

Molecular Weight

556.50

References & Citations

[1]P Loupias, et al. Synthesis and study of new siderophore analog-ciprofloxacin conjugates with antibiotic activities against Pseudomonas aeruginosa and Burkholderia spp. Eur J Med Chem. 2023 Jan 5;245 (Pt 2) :114921.