Antibacterial agent 128
Antibacterial agent 128 is a siderophore analog-Ciprofloxacin conjugate with a cleavable linker. Antibacterial agent 128 shows antibiotic activities against P. aeruginosa (MIC values of 0.25-64 μg/mL) and B. pseudomallei (MIC values of 1-32 μg/mL).
Product Specifications
CAS Number
3059046-75-9
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antibacterial-agent-128.html
Solubility
10 mM in DMSO
Smiles
CC(OC(N1CCN(CC1)C2=CC3=C(C(C(C(O)=O)=CN3C4CC4)=O)C=C2F)=O)OC(C5=CC(C(O)=CN5)=O)=O
Molecular Formula
C26H25FN4O9
Molecular Weight
556.50
References & Citations
[1]P Loupias, et al. Synthesis and study of new siderophore analog-ciprofloxacin conjugates with antibiotic activities against Pseudomonas aeruginosa and Burkholderia spp. Eur J Med Chem. 2023 Jan 5;245 (Pt 2) :114921.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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