Mal-Pc
Mal-Pc is a versatile molecular photosensitizer designed based phthalocyanine and maleimides. Mal-Pc can react with GSH to deplete GSH and reduce aggregation, thereby improving ROS (Reactive Oxygen Species) -mediated effect of photodynamic therapy (PDT) in cancer cells[1].
Product Specifications
CAS Number
2670367-74-3
UNSPSC
12352005
Target
Reactive Oxygen Species (ROS)
Type
Reference compound
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mal-pc.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCC(O[Si]234(OC(CCN5C(C=CC5=O)=O)=O)N6C(C7=C(C6=NC(C8=C9C=CC=C8)=[N]4C9=N%10)C=CC=C7)=NC(C%11=C%12C=CC=C%11)=[N]2C%12=NC%13=C(C=CC=C%14)C%14=C%10N%133)=O)C=CC1=O
Molecular Formula
C46H28N10O8Si
Molecular Weight
876.86
References & Citations
[1]Juanjuan Chen, et al. Novel molecular photosensitizer with simultaneously GSH depletion, aggregation inhibition and accelerated elimination for improved and safe photodynamic therapy. Eur J Med Chem. 2023 Jan 5;245 (Pt 1) :114938.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![MOX1 (MEOX1) Mouse Monoclonal Antibody [Clone ID: LBI2F4]](https://cdn.genprice.uk/genprice/uk/genprice4.webp)
AMM16625VCF 100 µg
MOX1 (MEOX1) Mouse Monoclonal Antibody [Clone ID: LBI2F4]
Sign In for Pricing
View Details 
244141-ML750 100 µL
CACNA1I (Calcium Channel, Voltage-Dependent, T Type, alpha 1I Subunit, Cav3.3, KIAA1120) (MaxLight 750) discontinued
Sign In for Pricing
View Details 
