Mal-Pc
Product Specifications
UNSPSC Description
Mal-Pc is a versatile molecular photosensitizer designed based phthalocyanine and maleimides. Mal-Pc can react with GSH to deplete GSH and reduce aggregation, thereby improving ROS (Reactive Oxygen Species)-mediated effect of photodynamic therapy (PDT) in cancer cells[1].
Target Antigen
Reactive Oxygen Species
Type
Reference compound
Related Pathways
Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/mal-pc.html
Solubility
10 mM in DMSO
Smiles
O=C(N1CCC(O[Si]234(OC(CCN5C(C=CC5=O)=O)=O)N6C(C7=C(C6=NC(C8=C9C=CC=C8)=[N]4C9=N%10)C=CC=C7)=NC(C%11=C%12C=CC=C%11)=[N]2C%12=NC%13=C(C=CC=C%14)C%14=C%10N%133)=O)C=CC1=O
Molecular Weight
876.86
References & Citations
[1]Juanjuan Chen, et al. Novel molecular photosensitizer with simultaneously GSH depletion, aggregation inhibition and accelerated elimination for improved and safe photodynamic therapy. Eur J Med Chem. 2023 Jan 5;245(Pt 1):114938.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-151940/Mal-Pc-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-151940/
Clinical Information
No Development Reported
CAS Number
2670367-74-3
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