Anti-inflammatory agent 33
Anti-inflammatory agent 33 is a potent p38α inhibitor. Anti-inflammatory agent 33 inhibits NO production. Anti-inflammatory agent 33 inhibits LPS-induced iNOS, COX-2, p-p38α, p-MK2 protein expression. Anti-inflammatory agent 33 shows anti-inflammatory activity[1].
Product Specifications
CAS Number
2816993-09-4
UNSPSC
12352005
Target
P38 MAPK
Type
Reference compound
Related Pathways
MAPK/ERK Pathway
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/anti-inflammatory-agent-33.html
Solubility
10 mM in DMSO
Smiles
COC1=CC=C(C=C1)S(=O)(NC2=CC3=C(N=C4C(C5=CC=CC=C5N4C3=O)=O)C=C2)=O
Molecular Formula
C22H15N3O5S
Molecular Weight
433.44
References & Citations
[1]Du J, et al. Novel tryptanthrin derivatives with benzenesulfonamide substituents: Design, synthesis, and anti-inflammatory evaluation. Eur J Med Chem. 2022 Nov 25;246:114956.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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