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Anti-inflammatory agent 33

Anti-inflammatory agent 33 is a potent p38α inhibitor. Anti-inflammatory agent 33 inhibits NO production. Anti-inflammatory agent 33 inhibits LPS-induced iNOS, COX-2, p-p38α, p-MK2 protein expression. Anti-inflammatory agent 33 shows anti-inflammatory activity[1].

Product Specifications

CAS Number

2816993-09-4

UNSPSC

12352005

Target

P38 MAPK

Type

Reference compound

Related Pathways

MAPK/ERK Pathway

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/anti-inflammatory-agent-33.html

Solubility

10 mM in DMSO

Smiles

COC1=CC=C(C=C1)S(=O)(NC2=CC3=C(N=C4C(C5=CC=CC=C5N4C3=O)=O)C=C2)=O

Molecular Formula

C22H15N3O5S

Molecular Weight

433.44

References & Citations

[1]Du J, et al. Novel tryptanthrin derivatives with benzenesulfonamide substituents: Design, synthesis, and anti-inflammatory evaluation. Eur J Med Chem. 2022 Nov 25;246:114956.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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