Antitumor agent-82

Antitumor agent-82 (compound 6g) is a potent anti-tumor agent. Antitumor agent-82 shows anti-proliferative activity. Antitumor agent-82 induces cell Autophagy by the ATG5/ATG7 signaling pathway[1].

Product Specifications

CAS Number

[3037605-45-8]

UNSPSC

12352005

Target

Atg7; Autophagy

Type

Reference compound

Related Pathways

Autophagy

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/antitumor-agent-82.html

Solubility

10 mM in DMSO

Smiles

CN1CCN(CC1)CC2=NC(CN3CCN(CC3)C)=C4C(C5=C(N4CCCC6=CC=CC=C6)C=CC=C5)=C2

Molecular Formula

C32H42N6

Molecular Weight

510.72

References & Citations

[1]Ao J, et al. Design, synthesis and pharmacological evaluation of β-carboline derivatives as potential antitumor agent via targeting autophagy. Eur J Med Chem. 2022 Nov 26;246:114955.