A3AR modulator 1
A3AR modulator 1 (MRS8054) is an orally active A3 adenosine receptor (A3AR) (Adenosine Receptor) positive allosteric modulator (PAM) . A3AR modulator 1 greatly enhances Cl-IB-MECA-stimulated [35S]GTPγS binding Emax[1].
Product Specifications
CAS Number
2991693-62-8
UNSPSC
12352005
Target
Adenosine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/a3ar-modulator-1.html
Solubility
10 mM in DMSO
Smiles
CCCC(C1=NC2=C(C3=C(N=C2NC4=CC=C(C=C4)I)C=CC=C3)N1)CCC
Molecular Formula
C23H25IN4
Molecular Weight
484.38
References & Citations
[1]Lucas B Fallot, e al. Structure-Activity Studies of 1 H-Imidazo[4,5- c]quinolin-4-amine Derivatives as A3 Adenosine Receptor Positive Allosteric Modulators. J Med Chem. 2022 Nov 24;65 (22) :15238-15262.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Adenosine A3 receptor (A3R)
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Tert-Butyl 7-Cyano-5-Oxa-2-Azaspiro[3.4]Octane-2-Carboxylate](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
FDC76336-01 50 mg
Tert-Butyl 7-Cyano-5-Oxa-2-Azaspiro[3.4]Octane-2-Carboxylate
Sign In for Pricing
View Details FDC76336-02 0.5 g
Tert-Butyl 7-Cyano-5-Oxa-2-Azaspiro[3.4]Octane-2-Carboxylate
Sign In for Pricing
View Details